ASUREX-A100 Regenerator

ion chromatography

Published case study of analytical quality by design method development and validation

Diduco has published a scientific peer-reviewed case study on how modern analytical method development can be performed in the pharmaceutical industry. The work was performed according to analytical quality by design (AQbD) principles to establish the design space and robust setpoint of the ion chromatography assay, and then validated according to the guidelines established by the International Council for Harmonization (ICH).

ion chromatography

Determination of sulfamate and sulfate in topiramate tablets according to USP monograph

Official quality control method for the second-generation antiepileptic drug topiramate which also have shown effect against migranes. This analysis was performed according to the United States Pharmacopeia monograph and determines the degradation products sulfamate and sulfate which can be formed during storage in humid environments or at elevated temperatures.

ion chromatography

Separation of glyphosate and related herbicides in aqueous samples

Analysis of glyphosate and related phosphonates acting as systemic herbicides is critical for protecting public health, ensuring regulatory compliance, and monitoring environmental safety. Because these chemicals are persistent, polar, and highly prevalent in agricultural ecosystems, detecting them allows management of dietary exposure and long-term health risks.

ion chromatography

Quantification of common anions in beer using a passivated HPLC system

Determination of anions in beer is relevant to brewers since their presence and concentration may impact the production processes and taste. High sulfate levels affect the taste of hopped beers, and chloride ions may contribute to the perceived sweetness. Nitrate and chloride ions can affect the yeast and have a negative impact on the fermentation process.

Ionrganic anions in bottled drinking water

ion chromatography

Quantification of common anions in drinking water according to EPA method 300.0A

Older version of the official procedure for quality control of drinking water according to the United States Environmental Protection Agency.

ion chromatography

Partial separation of structurally similar organic acids at isocratic conditions

Small organic acids are an important group of chemical compounds that needs to be analysed and quantified in many different industries. This application shows ion chromatography of a variety of organic acids using a non-optimized isocratic carbonate-based eluent.