We help you develop and improve analysis methods for polar compounds

Our friendly team with extensive experience in chromatography analysis in science and industry applications is here to help.

Services

We provide services for control laboratories, R&D departments and instrument distributors all over the world, while having our base in the north of Europe. Diduco is an independent research partner and we pride ourselves with quick service adapted to your needs. 

Screening

Don't know what separation mode, equipment or column is needed for your next analysis?

Get it right from the start by letting Diduco perform the initial screening. Then you optimize the method and take all the credit.

Development

Busy schedule? New technique for your laboratory? Just lazy?

Diduco can develop methods for you regardless of why. Spend your time and resources where you excel and let us assist with the other steps of the development.

Troubleshooting

Need a discussion partner to improve that problematic or unstable analysis method?

With experience from many industries, methods, and sample matrixes, Diduco is ready to help improve your analysis method.

Optimization

Perplexed by the numerous options of conditions?

Let Diduco assist with experimental design and multivariate data analysis to determine the critical factors, map your design space and find the method's robust setpoint.

Validation

Want a second laboratory
to verify your method?

Contract Diduco to check that your method meets pharmacopoeia requirements or ICH guidelines for specificity, linearity, recovery, precision, repeatability, robustness, accuracy, detection limit, etc.

Analysis

Desperate for results but don’t have the equipment or time?

Get your sample results delivered directly to your desk by letting Diduco perform the chemical analysis. Could be organic acids, carbohydrates, inorganic ions, or other small molecules.

Analytical quality by design

Read Diduco’s published case study of analytical quality by design (AQbD):

Validated modernized assay for foscarnet in pharmaceutical formulations using suppressed ion chromatography developed through a quality by design approach.

Get in contact
I’ll be happy to answer any questions you might have regarding our products and services.

Tobias Jonsson
CEO, PhD in chemistry
Mobile: +46 705783490
E-mail: tobias@diduco.com

Liquid chromatography techniques

Diduco focus on analytical techniques that can separate charged and neutral polar compounds in a reliable manner. Our laboratory is equipped with a range of HPLC instruments with different detectors to perform method development and analysis using techniques such as ion chromatography, hydrophilic interaction chromatography and ion exclusion chromatography, plus traditional reversed-phase.

IC

Ion Chromatography with suppressed conductivity detection is a highly sensitive technique for quantification of strong acids and inorganic ions. The approach enables analysis of many different sample types, ranging from water and battery electrolyte components, to beverages and pharmaceutical formulations.

HILIC

Hydrophilic Interaction Chromatography can be combined with detector types such as light absorption, evaporative light scattering, charged aerosol and mass spectrometry into a powerful analysis tool for an wide range of different polar charged and neutral molecules in a diversity of samples and situations.

IEC / ICE

Ion Exclusion Chromatography separates ionizable molecules based on their acidity or basicity by partial exclusion from an internal pore space. Detection techniques can range from compound specific light absorption and conductivity, to rather low-sensitivity eluent bulk features such as refractive index.

Typical analytes

Diduco specialises in analysis of charged and neutral polar compounds. This includes different inorganic anions, a range of organic acids, several sorts of carbohydrates and amino acids, plus a diversity of other hydrophilic molecules.

phosphate

Inorganic ions

Suppressed IC is typically the go-to technique for analysis of inorganic ions such as fluoride, chloride and sulfate.

organicacids2

Organic acids

IC, ICE and HILIC - all can be used for analysis of organic acids dependig on the sample and the method demands.

Glycerinaldehyd

Carbohydrates

IC, ICE and HILIC are all suitable for simple carbohydrates, whereas glycan complexes typically require HILIC.

Methionine

Amino acids

Amino acids and other zwitterionic compounds can be analyzed by HILIC without any derivatization.

Focus industries

Modern healthcare depends on strict quality control and analyses determining identity and concentrations of active ingredients, impurities, raw materials, counterions and other excipients in pharmaceutical formulations. Diduco contributes by providing reliable products and developing new methods following the ICH guidelines.

Ensuring that water, juice, beer, wine and other beverages, dietary supplements and food ingredients, contain low levels of contaminants and are safe to eat, but include the stated amounts of nutrients, is of primary concern to ensure a healthy life for people. 

Producing and storing energy in an efficient, reliable and sustainable manner is a monumental challenge for mankind. In energy plants and battery electrolytes it is therefore important to monitor contaminants and degradation products, since they are likely to affect the productivity, safety and duration of the systems.

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