organic acids – Diduco

Ion chromatography

Analysis of dietary supplement capsules with carnitine using a generic method for counterions

Oral L-carnitine is a dietary supplement that has been shown to reduce fatigue in elderly people with low muscular endurance, but its effects on athletes during physical activity are not well-supported. Although this endogenous compound is well-known for its involvement in the mitochondrial oxidation of long-chain fatty acids, no scientific evidence has been found that carnitine in isolation enhances fat-burning.

Ion-exclusion chromatography

Separation of organic acids by ion-exclusion chromatography

Separation of organic acids can be a challenging task due to their hydrophilic nature and structural diversity. One of the more traditional approaches to this analysis is ion exclusion chromatography, which offer complementary selectivity to other separation techniques, especially for the monovalent acids which tend to be more strongly retained in this mode.

Pharamaceutical counterions with XAMS suppressor and ASUREX-A200

Ion chromatography

Generic method for isocratic separation of fifteen common pharmaceutical counterions

Many medicines and dietary supplements are bases that carry a positive charge, and consequently these small molecules are accompanied by negatively charged counterions. Such anionic excipients may influence the properties of the pharmaceutical formulation and can also influence the effect of the active ingredient since different ion pairs can have different dissolution rates or abilities to penetrate cell walls.

Hydroxide gradient separation of organic acids and inorganic anions

Ion chromatography

Hydroxide gradient elution of organic acids and inorganic anions

Gradient elution is a powerful tool when aiming to separate many compounds having a wide range of different chemical characteristics. Hydroxide gradients are the most common in ion chromatography since they can be converted into pure water with nearly zero conductivity.

Ion chromatography

Generic method for isocratic separation of ten common pharmaceutical counterions

Ion chromatography

Partial separation of structurally similar organic acids at isocratic conditions

Small organic acids are an important group of chemical compounds that needs to be analysed and quantified in many different industries. This application shows ion chromatography of a variety of organic acids using a non-optimized isocratic carbonate-based eluent.

Ion chromatography

Separation of seven anions and acetate using IonPac AS22 column

Separation of inorganic anion standards at eluent conditions recommended by the column manufacturer.

Ion chromatography

Separation of seven anions and acetate using IonPac AS14 column

Separation of inorganic anion standards at eluent conditions recommended by the column manufacturer.

Keyword: organic acids

Applications

Analysis of dietary supplement capsules with carnitine using a generic method for counterions

Separation of organic acids by ion-exclusion chromatography

Generic method for isocratic separation of fifteen common pharmaceutical counterions

Hydroxide gradient elution of organic acids and inorganic anions

Generic method for isocratic separation of ten common pharmaceutical counterions

Partial separation of structurally similar organic acids at isocratic conditions

Separation of seven anions and acetate using IonPac AS22 column

Separation of seven anions and acetate using IonPac AS14 column

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