Excipient are all other substances formulated together with the active ingredient into a medication. Since pharmaceutical regulations require that all ingredients are proven to be safe, analysis of excipients are frequently performed.
Because many active ingredients are small molecule bases that carry a positive charge, these molecules are formulated together with negatively charged counterion excipients. Counterions are often quantified using ion chromatography (IC), but also ion-exclusion chromatography (IEC / ICE), hydrophilic interaction chromatography (HILIC), and even reversed phase (RP) HPLC may be more appropriate depending on the nature of the anion, the composition of the formulation, and the analysis requirements.
To learn more, browse the application examples below or contact Diduco to discuss your specific analysis.
Get in contact
I’ll be happy to answer any questions you might have regarding our products and services.
Tobias Jonsson
CEO, PhD in chemistry
Mobile: +46 705783490
E-mail: tobias@diduco.com
Diduco is a leading provider of professional services in high performance liquid chromatography and manufacturer of the Xenoic® XAMS chemical suppressor and ASUREX automatic regenerator for ion chromatography.
Diduco AB
Tvistevägen 48C
90736 Umeå
Sweden