Analyte: fumarate

Applications

ion chromatography

Generic method for isocratic separation of fifteen common pharmaceutical counterions

Many medicines and dietary supplements are bases that carry a positive charge, and consequently these small molecules are accompanied by negatively charged counterions. Such anionic excipients may influence the properties of the pharmaceutical formulation and can also influence the effect of the active ingredient since different ion pairs can have different dissolution rates or abilities to penetrate cell walls.

ion chromatography

Column screening using hydroxide gradients for ion chromatography method development

Hydroxide gradient elution is an effective approach in ion chromatography analysis due to its ability to separate organic acids and anions with a wide range of characteristics. During method development of such protocols, scouting gradients is a quick way to rapidly screen different columns and assess their potential for a certain analysis situation and sample composition.

ion chromatography

Generic method for isocratic separation of ten common pharmaceutical counterions

ion chromatography

Partial separation of structurally similar organic acids at isocratic conditions

Small organic acids are an important group of chemical compounds that needs to be analysed and quantified in many different industries. This application shows ion chromatography of a variety of organic acids using a non-optimized isocratic carbonate-based eluent.

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