Topic: tablets

Applications

  • ion chromatography

Determination of sulfamate and sulfate in topiramate tablets according to USP monograph

Official quality control method for the second-generation antiepileptic drug topiramate which also have shown effect against migranes. This analysis was performed according to the United States Pharmacopeia monograph and determines the degradation products sulfamate and sulfate which can be formed during storage in humid environments or at elevated temperatures.
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